Leptin: A pubertal hormone in obese and non-obese children? • 15
نویسندگان
چکیده
منابع مشابه
Hormone replacement therapy affects body composition and leptin differently in obese and non-obese postmenopausal women.
Leptin and oestrogen are both involved in the regulation of adipose tissue deposition and feeding behaviour. We investigated whether 5 years of hormone replacement therapy (HRT) affected serum leptin and body composition differently in 89 postmenopausal women treated with HRT compared with 178 controls. At baseline, leptin was significantly correlated with oestradiol (r=0.13, P<0.05) and in mul...
متن کاملThe metabolome profiling of obese and non-obese individuals: Metabolically healthy obese and unhealthy non-obese paradox
Objective(s): The molecular basis of “metabolically healthy obese” and “metabolically unhealthy non-obese” phenotypes is not fully understood. Our objective was to identify metabolite patterns differing in obese (metabolically healthy vs unhealthy (MHO vs MUHO)) and non-obese (metabolically healthy vs unhealthy (MHNO vs MUHNO)) individuals. Materials ...
متن کاملThe Role of Leptin in Obese Children
The obesity gene (ob) in mice encodes a protein produced by adipose tissue, leptin, which regulates body weight (3). Under experimental conditions, leptin affects the central nervous system and tends to reduce appetite and increase energy expenditure. Numerous studies have shown an increased expression of the ob gene (mRNA-leptin) in adipocytes or a marked increase in serum leptin concentration...
متن کاملComparative Evaluation of Iron Deficiency among Obese and Non-obese Children
Background Obese children are at the risk of micronutrient deficiency especially iron deficiency. Given the importance of iron deficiency in this age group and considering the existing discrepancies, present study was performed with the aim of evaluating iron deficiency in obese children. Material and Method This study was conducted, in the form of a case-control study, on 100 children aged...
متن کاملUpdate on statural growth and pubertal development in obese children
Childhood obesity is a growing and alarming problem, associated with several short-term and long-term metabolic and cardiovascular complications. In addition, it has also been suggested that excess adiposity during childhood influences growth and pubertal development. Several studies have shown that during pre-pubertal years, obese patients present higher growth velocity and that this pre-puber...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1997
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199704001-00036